RAMPing up voltage indicator imaging

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Two-photon voltage imaging using a genetically encoded voltage indicator

Voltage-sensitive fluorescent proteins (VSFPs) are a family of genetically-encoded voltage indicators (GEVIs) reporting membrane voltage fluctuation from genetically-targeted cells in cell cultures to whole brains in awake mice as demonstrated earlier using 1-photon (1P) fluorescence excitation imaging. However, in-vivo 1P imaging captures optical signals only from superficial layers and does n...

متن کامل

Ramping up assessment at the UNLV Libraries

Assessment activities at UNLV Libraries have strengthened and diversified over the last several years, thanks to several factors including the guidance of its Dean, the development of technology and human infrastructure, the impact of implementing the LibQual+ survey, and other factors. Signs of its place in the Libraries can be seen in the Libraries’ Strategic Plan and a recent review of the S...

متن کامل

Comparative performance of a genetically-encoded voltage indicator and a blue voltage sensitive dye for large scale cortical voltage imaging

Traditional small molecule voltage sensitive dye indicators have been a powerful tool for monitoring large scale dynamics of neuronal activities but have several limitations including the lack of cell class specific targeting, invasiveness and difficulties in conducting longitudinal studies. Recent advances in the development of genetically-encoded voltage indicators have successfully overcome ...

متن کامل

Ramping up evidence-based ventricular assist device care.

Over the past several decades, mechanical circulatory support has become an increasingly important treatment for patients with advanced heart failure. Initial proof-of-concept trials focused on reducing the mortality of critically ill patients in cardiogenic shock. Although the ultimate goal of mechanically assisted circulation was always long-term support as an alternative to cardiac transplan...

متن کامل

Ramping up policy measures in the area of physical activity.

The American population weighs too much. That is so well documented; it does not even need a citation. And for all the millions of pages of research and gray literature devoted to the topic and all the complex reasons for American obesity, we know that Americans tend to eat too much, and too much of the wrong things, while not exercising nearly enough. With the girth of America growing, taking ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nature Methods

سال: 2020

ISSN: 1548-7091,1548-7105

DOI: 10.1038/s41592-019-0720-4